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DPOD4 rabbit pAb

CAT: 0855-ES9592-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9592-01Size:50 µL
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Background
This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
Description
This gene encodes the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],
UniProt
Q9HCU8
Swiss Prot
Q9HCU8
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein AA range: 1-50
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
11kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
11kD
Fragment
IgG
Subcellular Location
Nucleus . Partially recruited to DNA damage sites within 2 hours following UV irradiation, before degradation. .
Gene ID (Human)
57804