Products for Research Use Only
RegisterLogin

CAMLG rabbit pAb

CAT: 0855-ES9465-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES9465-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]
Description
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008],
UniProt
P49069
Swiss Prot
P49069
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
CAMLG
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
32kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
32kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
Gene ID (Human)
819

Related Products

CatalogName
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb
ES20826-01ATG5 Rabbit rabbit pAb
ES20659-01NBR1 Rabbit rabbit pAb
ES20825-01ATG7 Rabbit rabbit pAb

Alternative Products

CatalogName
MBS8549197-01CAMLG Rabbit pAb
H00000819-D01PRabbit Polyclonal CAMLG Antibody
GTR17871242CAMLG Rabbit Polyclonal Antibody
MBS8554555-01CAMLG (Center) Rabbit pAb
GTR18054479-01CAMLG rabbit pAb Antibody
APR20290N-01CAMLG Rabbit pAb (APR20290N)
GTR18613765CAMLG Rabbit Polyclonal Antibody (Biotin)
GTR18373212CAMLG Rabbit Polyclonal Antibody (FITC)
520889-01CAMLG

Popular Products