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ACSA rabbit pAb

CAT: 0855-ES9338-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9338-02Size:100 µL
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Background
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
Description
This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],
UniProt
Q9NR19
Swiss Prot
Q9NR19
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
77kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
77kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol .
Gene ID (Human)
55902

UniProtKB · Q9NR19

Acetyl-coenzyme A synthetase, cytoplasmic

ACSA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NR19
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ACSS2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
6.2.1.1
Processing
—
Secondary accessions
A6NE90, Q5QPH2, Q5QPH3, Q8N238, Q96EL0, Q9NQP7, Q9UJ15
Protein keywords

PTM

AcetylationPhosphoprotein

Molecular function

ActivatorLigase

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmNucleus

Biological process

Lipid metabolismTranscriptionTranscription regulation

Technical term

Proteomics identificationReference proteome

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