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RL7A rabbit pAb

CAT: 0855-ES9329-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9329-02Size:100 µL
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Background
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene t
Description
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene t
UniProt
P62424
Swiss Prot
P62424
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Target
RL7A
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
29kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
29kD
Fragment
IgG
Subcellular Location
Nucleus, nucleolus, cytoplasm, cytosol, ribosome, cell-cell adherens junction, focal adhesion, membrane, cytosolic large ribosomal subunit, polysomal ribosome, extracellular exosome
Gene ID (Human)
6130

UniProtKB · P62424

Large ribosomal subunit protein eL8

RL7A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P62424
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
RPL7A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
P11518, Q5T8U4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondUbl conjugation

Coding sequence diversity

Chromosomal rearrangement

Cellular component

Cytoplasm

Molecular function

RibonucleoproteinRibosomal protein

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