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ITBP2 rabbit pAb

CAT: 0855-ES9183-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9183-02Size:100 µL
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Background
Domain:The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca (2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein., function:May play a role during maturation and/or organization of muscles cells., similarity:Contains 1 CS domain., similarity:Contains 2 CHORD domains., subunit:Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium., tissue specificity:Expressed in skeletal and cardiac muscles but not in other tissues.
Description
Domain: The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca (2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein. function: May play a role during maturation and/or organization of muscles cells. similarity: Contains 1 CS domain. similarity: Contains 2 CHORD domains. subunit: Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium. tissue specificity: Expressed in skeletal and cardiac muscles but not in other tissues.
UniProt
Q9UKP3
Swiss Prot
Q9UKP3
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Target
ITBP2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
38kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
38kD
Fragment
IgG
Subcellular Location
Z disc
Gene ID (Human)
26548

UniProtKB · Q9UKP3

Integrin beta-1-binding protein 2

ITBP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UKP3
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ITGB1BP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q32N04, Q549J7
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

Metal-bindingZinc

Technical term

Proteomics identificationReference proteome

Domain

RepeatSH3-binding

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