ITBP2 rabbit pAb

• Background :

  Domain:The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca (2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein., function:May play a role during maturation and/or organization of muscles cells., similarity:Contains 1 CS domain., similarity:Contains 2 CHORD domains., subunit:Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium., tissue specificity:Expressed in skeletal and cardiac muscles but not in other tissues.

• Description :

  Domain: The tail domain binds to the cytoplasmic domain of both integrin beta-1a and beta-1d isoforms. The presence of Ca (2+) ions does not prevent binding of a fragment consisting of the second cysteine rich repeat and the tail domain but prevents the binding of the full-length protein. function: May play a role during maturation and/or organization of muscles cells. similarity: Contains 1 CS domain. similarity: Contains 2 CHORD domains. subunit: Interacts with beta-1 integrin subunit. This interaction is regulated by divalent cations, and it occurs only in absence of calcium. tissue specificity: Expressed in skeletal and cardiac muscles but not in other tissues.

• UniProt :

  Q9UKP3

• Swiss Prot :

  Q9UKP3

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 10-90

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  38kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  38kD

• Fragment :

  IgG

• Subcellular Location :

  Z disc

• Gene ID (Human) :

  26548