Products for Research Use Only
RegisterLogin

INCE rabbit pAb

CAT: 0855-ES9002-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES9002-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger, ' or transiently interacting, proteins (reviewed by Choo, 1997) . The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142) . The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]) . These include CENPE (MIM 117143) ; MCAK (MIM 604538) ; KID (MIM 603213) ; cytoplasmic dynein (e.g., MIM 600112) ; CliPs (e.g., MIM 179838) ; and CENPF/mitosin (MIM 600236) . The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization alo
Description
In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger, ' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cytoplasmic dynein (e. g. MIM 600112); CliPs (e. g. MIM 179838); and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization alo
UniProt
Q9NQS7
Swiss Prot
Q9NQS7
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
100kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
100kD
Fragment
IgG
Subcellular Location
Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle . Midbody . Chromosome, centromere, kinetochore . Colocalized at synaptonemal complex central element from zygotene up to late pachytene when it begins to relocalize to heterochromatic chromocenters. Colocalizes with AURKB at a connecting strand traversing the centromere region and joining sister kinetochores, in metaphase II centromeres. This strand disappears at the metaphase II/anaphase II transition and relocalizes to the spindle midzone (By similarity) . Colocalizes with AURKB at mitotic chromosomes (PubMed:11453556) . Localizes to inner kinetochore (PubMed:16760428) . Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase
Gene ID (Human)
3619

Related Products

CatalogName
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb
ES20826-01ATG5 Rabbit rabbit pAb
ES20659-01NBR1 Rabbit rabbit pAb
ES20825-01ATG7 Rabbit rabbit pAb

Alternative Products

CatalogName
MBS9515000-01INCE Rabbit Polyclonal Antibody
PAV1873Rabbit Anti-INCE/SNX5 Polyclonal Antibody
537938-01INCE discontinued
C44251-01INCE Antibody
BT-AP10378-01INCE Polyclonal Antibody
506386Ince Normal Breast Media (Ince BMI-P) (Liquid)
STJ190160Anti-INCE antibody
506392Ince Primary T-Cell Leukemia Media (Ince TLMI) (Liquid)
506388Ince Normal or Transformed Ovary and Fallopian Tube Media (Ince FOMI) (Liquid)
506391Ince Primary Endometrioid and Mucinous Ovarian Cancer Media (Ince OCMI-Le) (Liquid)

Popular Products