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PEX14 rabbit pAb

CAT: 0855-ES8932-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8932-02Size:100 µL
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Background
Peroxisomal biogenesis factor 14 (PEX14) Homo sapiens This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008]
Description
Peroxisomal biogenesis factor 14 (PEX14) Homo sapiens This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome. [provided by RefSeq, Jul 2008],
Product Name Alternative
Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14)
UniProt
O75381
Swiss Prot
O75381
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human PEX14 Polyclonal
Target
PEX14
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
41kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
41kD
Fragment
IgG
Subcellular Location
Peroxisome membrane ; Peripheral membrane protein ; Cytoplasmic side .
Other Product Names
Peroxisomal membrane protein PEX14 (PTS1 receptor-docking protein) (Peroxin-14) (Peroxisomal membrane anchor protein PEX14)
Gene ID (Human)
5195

UniProtKB · O75381

Peroxisomal membrane protein PEX14

PEX14_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O75381
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PEX14
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B2R7N1, B3KML6, B7Z1N2, Q8WX51
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

MembranePeroxisome

Disease

Peroxisome biogenesis disorderZellweger syndrome

Biological process

Protein transportTranslocationTransport

Domain

TransmembraneTransmembrane helix