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OASL rabbit pAb

CAT: 0855-ES8870-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8870-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Caution:This may not be the true ortholog of mouse OASL., function:Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA., induction:By interferons., similarity:Belongs to the 2-5A synthetase family., similarity:Contains 2 ubiquitin-like domains., subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR) . TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1., tissue specificity:Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
Description
Caution: This may not be the true ortholog of mouse OASL. function: Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA. induction: By interferons. similarity: Belongs to the 2-5A synthetase family. similarity: Contains 2 ubiquitin-like domains. subunit: Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1. tissue specificity: Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.
Product Name Alternative
2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)
UniProt
Q15646
Swiss Prot
Q15646
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human OASL. at AA range: 1-50
Target
OASL
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Buffer
-20°C/1 year
Molecular Weight
60kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
60kD
Fragment
IgG
Subcellular Location
[Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm.
Other Product Names
2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)
Gene ID (Human)
8638

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