OASL rabbit pAb

• Background:

  Caution:This may not be the true ortholog of mouse OASL., function:Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA., induction:By interferons., similarity:Belongs to the 2-5A synthetase family., similarity:Contains 2 ubiquitin-like domains., subunit:Specifically interacts with the ligand binding domain of the thyroid receptor (TR) . TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1., tissue specificity:Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.

• Description:

  Caution: This may not be the true ortholog of mouse OASL. function: Does not have 2'-5'-OAS activity, but binds double-stranded RNA and DNA. induction: By interferons. similarity: Belongs to the 2-5A synthetase family. similarity: Contains 2 ubiquitin-like domains. subunit: Specifically interacts with the ligand binding domain of the thyroid receptor (TR). TRIP14 does not require the presence of thyroid hormone for its interaction. Binds MBD1. tissue specificity: Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis.

• UniProt:

  Q15646

• Swiss Prot:

  Q15646

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human OASL. at AA range: 1-50

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000, ELISA 1:10000-20000

• Molecular Weight:

  60kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  60kD

• Fragment:

  IgG

• Subcellular Location:

  [Isoform p56]: Nucleus, nucleolus. Cytoplasm.; [Isoform p30]: Cytoplasm.

• Other Product Names:

  2'-5'-oligoadenylate synthase-like protein (2'-5'-OAS-related protein) (2'-5'-OAS-RP) (59 kDa 2'-5'-oligoadenylate synthase-like protein) (Thyroid receptor-interacting protein 14) (TR-interacting protein 14) (TRIP-14) (p59 OASL) (p59OASL)

• Gene ID (Human):

  8638