OAS2 rabbit pAb

OAS2 rabbit pAb

• Description: 2'-5'-oligoadenylate synthetase 2 (OAS2) Homo sapiens This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2', 5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
• Synonyms: OAS2; 2'-5'-oligoadenylate synthase 2; (2-5')oligo(A) synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS; p69OAS / p71OAS
• Gene ID: 4939
• UniProt: P29728
• Cellular Locus: Cytoplasm. Cytoplasm, perinuclear region.
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse,
• Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human OAS2. AA range:61-110
• Clonality: Polyclonal
• Validated Applications: WB, IHC, IF, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000. Not yet tested in other applications.
• Molecular Weight: 82kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.