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GABA T-1 rabbit pAb

CAT: 0855-ES8587-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8587-01Size:50 µL
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Background
The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]) .[supplied by OMIM, Jul 2009]
Description
The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al. 2009 [PubMed 19077666]). [supplied by OMIM, Jul 2009],
UniProt
P30531
Swiss Prot
P30531
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human SLC6A1. AA range:170-220
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000
Molecular Weight
50kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
50kD
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Cell junction, synapse, presynapse . Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons (By similarity) . .
Other Product Names
Sodium- and chloride-dependent GABA transporter 1 (GAT-1; Solute carrier family 6 member 1)
Gene ID (Human)
6529

UniProtKB · P30531

Sodium- and chloride-dependent GABA transporter 1

SC6A1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P30531
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC6A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GAT-1
EC number
—
Processing
—
Secondary accessions
Q8N4K8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneCell projectionMembraneSynapse

Disease

Disease variantEpilepsy

PTM

Disulfide bondGlycoproteinPhosphoprotein

Ligand

Metal-bindingSodium

Biological process

Neurotransmitter transportSymportTransport

Domain

TransmembraneTransmembrane helix

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