RCC1 rabbit pAb
CAT:
855-ES8532-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
RCC1 rabbit pAb
- Description: Disease: Patients with Raynaud disease produce antibodies that bind to RCC1. function: Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. similarity: Contains 7 RCC1 repeats. subcellular location: Becomes dispersed throughout the cytoplasm during mitosis.
- Synonyms: RCC1 CHC1
- Gene ID: 1104
- UniProt: P18754
- Cellular Locus: Nucleus. Chromosome. Cytoplasm. Predominantly nuclear in interphase cells (PubMed:12194828). Binds to mitotic chromosomes (PubMed:12194828, PubMed:17435751, PubMed:20668449)..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Synthetic peptide from human protein at AA range: 301-350
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: WB 1:500-2000,IHC-p 1:50-200 ELISA 1:10000-20000
- Molecular Weight: 45kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.