DZIP3 rabbit pAb

• Background:

  Function:E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA., pathway:Protein modification; protein ubiquitination., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Contains 1 RING-type zinc finger., subunit:Interacts with DAZ proteins., tissue specificity:Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.

• Description:

  Function: E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA. pathway: Protein modification; protein ubiquitination. sequence Caution: Contaminating sequence. Potential poly-A sequence. similarity: Contains 1 RING-type zinc finger. subunit: Interacts with DAZ proteins. tissue specificity: Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.

• UniProt:

  Q86Y13

• Swiss Prot:

  Q86Y13

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human DZIP3. AA range:681-730

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  140kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  140kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm .

• Other Product Names:

  DZIP3; KIAA0675; E3 ubiquitin-protein ligase DZIP3; DAZ-interacting protein 3; RNA-binding ubiquitin ligase of 138 kDa; hRUL138

• Gene ID (Human):

  9666