Granuphilin rabbit pAb

Granuphilin rabbit pAb

• Description: This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Mar 2010],
• Synonyms: SYTL4; Synaptotagmin-like protein 4; Exophilin-2; Granuphilin
• Gene ID: 94121
• UniProt: Q96C24
• Cellular Locus: Membrane ; Peripheral membrane protein. Cell membrane ; Peripheral membrane protein. Cytoplasmic vesicle, secretory vesicle membrane ; Peripheral membrane protein. Detected close to the plasma membrane and on secretory granules. In pancreas, interacts with insulin-containing vesicles (By similarity)..
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human SYTL4. AA range:381-430
• Clonality: Polyclonal
• Validated Applications: WB, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
• Molecular Weight: 76kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.