ATG7 Rabbit rabbit pAb
CAT:
855-ES20825-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ATG7 Rabbit rabbit pAb
- Description: This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
- Synonyms: Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7;Autophagy-related protein 7;APG7-like;hAGP7;Ubiquitin-activating enzyme E1-like protein)
- Gene ID: 10533
- UniProt: O95352
- Cellular Locus: Cytoplasm. Preautophagosomal structure. Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: Recombinant Protein of ATG7
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: IHC-p 1:50-300,WB 1:500-2000
- Molecular Weight: 78kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.