CRIF1 rabbit pAb

• Background:

  This gene encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. The encoded protein may interact with other cell cycle regulators. [provided by RefSeq, Aug 2012]

• Description:

  This gene encodes a nuclear-localized protein that may be induced by p53 and regulates the cell cycle by inhibiting G1 to S phase progression. The encoded protein may interact with other cell cycle regulators. [provided by RefSeq, Aug 2012],

• Synonyms:

  GADD45GIP1; PLINP1; PRG6; Growth arrest and DNA damage-inducible proteins-interacting protein 1; CKII beta-associating protein; CR6-interacting factor 1; CRIF1; Papillomavirus L2-interacting nuclear protein 1; PLINP; PLINP-1; p53-responsive

• Gene ID:

  90480

• UniProt:

  Q8TAE8

• Cellular Locus:

  Mitochondrion. Nucleus. Using N-terminally tagged constructs, has been found in the nucleus (PubMed:12482659). C-terminally tagged constructs are targeted exclusively to mitochondria (PubMed:22453275). This discrepancy may be explained by masking of a potential N-terminal mitochondrial targeting signal by the tag (PubMed:22453275)..

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human GADD45GIP1. AA range:91-140

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IHC; IF; ELISA

• Validated Applications:

  IHC, IF, ELISA

• Stability:

  -20°C / 1 year

• Concentration:

  1 mg/mL

• Dilution:

  Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Mitochondrion . Nucleus . Using N-terminally tagged constructs, has been found in the nucleus (PubMed:12482659) . C-terminally tagged constructs are targeted exclusively to mitochondria (PubMed:22453275) . This discrepancy may be explained by masking of a potential N-terminal mitochondrial targeting signal by the tag (PubMed:22453275) . .

• Other Product Names:

  GADD45GIP1; PLINP1; PRG6; Growth arrest and DNA damage-inducible proteins-interacting protein 1; CKII beta-associating protein; CR6-interacting factor 1; CRIF1; Papillomavirus L2-interacting nuclear protein 1; PLINP; PLINP-1; p53-responsive

• Gene ID (Human):

  90480

• SwissProt (Human):

  Q8TAE8