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FMIP rabbit pAb

CAT: 0855-ES7821-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7821-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:May be involved in the differentiation of granulocytes and adipocytes., PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity) . Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the THOC5 family., subcellular location:Shuttles between nucleus and cytoplasm., subunit:Interacts with phosphorylated CSF1R., tissue specificity:Ubiquitously expressed.
Description
Function: May be involved in the differentiation of granulocytes and adipocytes. PTM: Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the THOC5 family. subcellular location: Shuttles between nucleus and cytoplasm. subunit: Interacts with phosphorylated CSF1R. tissue specificity: Ubiquitously expressed.
UniProt
Q13769
Swiss Prot
Q13769
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human THOC5. AA range:561-610
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
78kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
78kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Shuttles between nucleus and cytoplasm. .
Other Product Names
THOC5; C22orf19; KIAA0983; THO complex subunit 5 homolog; Functional spliceosome-associated protein 79; fSAP79; NF2/meningioma region protein pK1.3; Placental protein 39.2; PP39.2; hTREX90
Gene ID (Human)
8563

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