FMIP rabbit pAb

• Background :

  Function:May be involved in the differentiation of granulocytes and adipocytes., PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity) . Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the THOC5 family., subcellular location:Shuttles between nucleus and cytoplasm., subunit:Interacts with phosphorylated CSF1R., tissue specificity:Ubiquitously expressed.

• Description :

  Function: May be involved in the differentiation of granulocytes and adipocytes. PTM: Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the THOC5 family. subcellular location: Shuttles between nucleus and cytoplasm. subunit: Interacts with phosphorylated CSF1R. tissue specificity: Ubiquitously expressed.

• UniProt :

  Q13769

• Swiss Prot :

  Q13769

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human THOC5. AA range:561-610

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight :

  78kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  78kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Cytoplasm . Shuttles between nucleus and cytoplasm. .

• Other Product Names :

  THOC5; C22orf19; KIAA0983; THO complex subunit 5 homolog; Functional spliceosome-associated protein 79; fSAP79; NF2/meningioma region protein pK1.3; Placental protein 39.2; PP39.2; hTREX90

• Gene ID (Human) :

  8563