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NFATc2IP rabbit pAb

CAT: 0855-ES7785-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7785-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production., PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine production., similarity:Contains 1 ubiquitin-like domain., subcellular location:TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus., subunit:Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.
Description
Function: Plays a role in the inducible expression of Cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production. PTM: Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented Cytokine production. similarity: Contains 1 ubiquitin-like domain. subcellular location: TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. subunit: Interacts with NFATC2, TRAF1, TRAF2 and PRMT1.
UniProt
Q8NCF5
Swiss Prot
Q8NCF5
Reactivity
Human; Rat; Mouse; ; Fish
Immunogen
The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
48kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
48kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. .
Other Product Names
NFATC2IP; NIP45; NFATC2-interacting protein; 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; Nuclear factor of activated T-cells; cytoplasmic 2-interacting protein
Gene ID (Human)
84901

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