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Wee1 (phospho Ser642) rabbit pAb

CAT: 0855-ES7515-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7515-01Size:50 µL
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Background
WEE1 G2 checkpoint kinase (WEE1) Homo sapiens This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008]
Description
WEE1 G2 checkpoint kinase (WEE1) Homo sapiens This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase. [provided by RefSeq, Jul 2008],
Product Name Alternative
WEE1; Wee1-like protein kinase; WEE1hu; Wee1A kinase
UniProt
P30291
Swiss Prot
P30291
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human WEE1 around the phosphorylation site of Ser642. AA range:597-646
Target
WEE1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
100kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
100kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
WEE1; Wee1-like protein kinase; WEE1hu; Wee1A kinase
Gene ID (Human)
7465

UniProtKB · P30291

Wee1-like protein kinase

WEE1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P30291
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
WEE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
WEE1hu
EC number
2.7.10.2
Processing
—
Secondary accessions
B3KVE1, D3DQV0
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-binding

Biological process

Cell cycleCell divisionMitosis

Molecular function

KinaseTransferaseTyrosine-protein kinase

Cellular component

Nucleus

PTM

PhosphoproteinUbl conjugation

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