MtTFA rabbit pAb

• Background:

  This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

• Description:

  This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

• UniProt:

  Q00059

• Swiss Prot:

  Q00059

• Reactivity:

  Human; Rat; Mouse; ; Bovine

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human TFAM. AA range:131-180

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000; Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  22kd

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  22kd

• Fragment:

  IgG

• Subcellular Location:

  Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid .

• Other Product Names:

  TFAM; TCF6; TCF6L2; Transcription factor A; mitochondrial; mtTFA; Mitochondrial transcription factor 1; MtTF1; Transcription factor 6; TCF-6; Transcription factor 6-like 2

• Gene ID (Human):

  7019