Treacle rabbit pAb

CAT: 0855-ES7354-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES7354-01Size:50 µL
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Background
This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF) . Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Description
This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],
UniProt
Q13428
Swiss Prot
Q13428
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TCOF1. AA range:41-90
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
152kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
152kD
Fragment
IgG
Subcellular Location
Nucleus, nucleolus .
Other Product Names
TCOF1; Treacle protein; Treacher Collins syndrome protein
Gene ID (Human)
6949

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