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Tafazzin rabbit pAb

CAT: 0855-ES7346-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7346-01Size:50 µL
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Background
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC) . Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known. [provided by RefSeq, Jul 2008]
Description
This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known. [provided by RefSeq, Jul 2008],
UniProt
Q16635
Swiss Prot
Q16635
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from the Internal region of human Tafazzin.
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
33kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
33kD
Fragment
IgG
Subcellular Location
Mitochondrion outer membrane ; Peripheral membrane protein ; Intermembrane side . Mitochondrion inner membrane ; Peripheral membrane protein ; Intermembrane side .; [Isoform 1]: Mitochondrion membrane .; [Isoform 2]: Cytoplasm .; [Isoform 3]: Mitochondrion membrane .; [Isoform 5]: Mitochondrion membrane .; [Isoform 6]: Cytoplasm .; [Isoform 7]: Mitochondrion membrane .; [Isoform 8]: Cytoplasm .; [Isoform 9]: Cytoplasm .
Other Product Names
TAZ; EFE2; G4.5; Tafazzin; Protein G4.5
Gene ID (Human)
6901

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