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Sp2 rabbit pAb

CAT: 0855-ES7258-02Size: 100 µLDry Ice: NoHazardous: No
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Background
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008],
UniProt
Q02086
Swiss Prot
Q02086
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human SP2. AA range:471-520
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
64kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
64kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
SP2; KIAA0048; Transcription factor Sp2
Gene ID (Human)
6668

UniProtKB · Q02086

Transcription factor Sp2

SP2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q02086
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SP2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A6NK74
Protein keywords

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative splicing

Ligand

Metal-bindingZinc

Cellular component

Nucleus

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

Biological process

TranscriptionTranscription regulation

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