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POLR1E rabbit pAb

CAT: 0855-ES7174-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7174-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF., similarity:Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family., subunit:Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity) . Interacts with PAF49/CD3EAP. Also binds UBTF/UBF.
Description
Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors. Appears to be involved in the formation of the initiation complex at the promoter by mediating the interaction between Pol I and UBTF/UBF. similarity: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family. subunit: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits (By similarity). Interacts with PAF49/CD3EAP. Also binds UBTF/UBF.
UniProt
Q9GZS1
Swiss Prot
Q9GZS1
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from the Internal region of human POLR1E.
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
49kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
49kD
Fragment
IgG
Subcellular Location
Nucleus, nucleolus .
Other Product Names
POLR1E; PAF53; PRAF1; DNA-directed RNA polymerase I subunit RPA49; RNA polymerase I subunit A49; DNA-directed RNA polymerase I subunit E; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53
Gene ID (Human)
64425

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