Products for Research Use Only
RegisterLogin

POLR3B rabbit pAb

CAT: 0855-ES6747-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES6747-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Description
This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
UniProt
Q9NW08
Swiss Prot
Q9NW08
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human POLR3B. AA range:321-370
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
128kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
128kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
POLR3B; DNA-directed RNA polymerase III subunit RPC2; RNA polymerase III subunit C2; C128; DNA-directed RNA polymerase III 127.6 kDa polypeptide; DNA-directed RNA polymerase III subunit B
Gene ID (Human)
55703

UniProtKB · Q9NW08

DNA-directed RNA polymerase III subunit RPC2

RPC2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NW08
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POLR3B
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
RNA polymerase III subunit C2
EC number
2.7.7.6
Processing
—
Secondary accessions
A8K6H0, B3KV73, F5H1E6, Q9NW59
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Antiviral defenseImmunityInnate immunityTranscription

Disease

Charcot-Marie-Tooth diseaseDisease variantLeukodystrophyNeurodegenerationNeuropathy

Cellular component

CytoplasmDNA-directed RNA polymeraseNucleus

Ligand

MagnesiumMetal-bindingZinc

Molecular function

NucleotidyltransferaseTransferase

Domain

Zinc-finger

Related Products

CatalogName
ES4219-01POLR3G rabbit pAb
ES7244-01POLR3D rabbit pAb
ES4523-01POLR3C rabbit pAb
ES3244-01POLR3E rabbit pAb
ES3243-01POLR3A rabbit pAb
ES5004-01POLR3H rabbit pAb
ES6649-01POLR2E rabbit pAb
ES7174-01POLR1E rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb

Alternative Products

CatalogName
E45R19289NPOLR3B Rabbit pAb
NBP3-06317-50ulRabbit Polyclonal POLR3B Antibody
TA315598POLR3B Rabbit Polyclonal Antibody
MBS4512364-01Rabbit anti-POLR3B Antibody
APR19289N-01POLR3B Rabbit pAb (APR19289N)
NBP3-06317PCPRabbit Polyclonal POLR3B Antibody [PerCP]
NBP3-06317FRabbit Polyclonal POLR3B Antibody [FITC]
NBP3-06317BRabbit Polyclonal POLR3B Antibody [Biotin]
GTR18371672POLR3B Rabbit Polyclonal Antibody (FITC)
GTR18371673POLR3B Rabbit Polyclonal Antibody (Biotin)

Popular Products