Tip5 rabbit pAb

• Background :

  Function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the WAL family., similarity:Contains 1 bromo domain., similarity:Contains 1 DDT domain., similarity:Contains 1 MBD (methyl-CpG-binding) domain., similarity:Contains 1 PHD-type zinc finger., similarity:Contains 4 A.T hook DNA-binding domains., subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus., subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex) ., tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.

• Description :

  Function: May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. sequence Caution: Contaminating sequence. Potential poly-A sequence. similarity: Belongs to the WAL family. similarity: Contains 1 bromo domain. similarity: Contains 1 DDT domain. similarity: Contains 1 MBD (methyl-CpG-binding) domain. similarity: Contains 1 PHD-type zinc finger. similarity: Contains 4 A. T hook DNA-binding domains. subcellular location: Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus. subunit: Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex). tissue specificity: Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.

• UniProt :

  Q9UIF9

• Swiss Prot :

  Q9UIF9

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human BAZ2A. AA range:1281-1330

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Molecular Weight :

  210kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  210kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus, nucleolus . Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus. .

• Other Product Names :

  BAZ2A; KIAA0314; TIP5; Bromodomain adjacent to zinc finger domain protein 2A; Transcription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3

• Gene ID (Human) :

  605682