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Tip5 rabbit pAb

CAT: 0855-ES7056-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7056-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Contaminating sequence. Potential poly-A sequence., similarity:Belongs to the WAL family., similarity:Contains 1 bromo domain., similarity:Contains 1 DDT domain., similarity:Contains 1 MBD (methyl-CpG-binding) domain., similarity:Contains 1 PHD-type zinc finger., similarity:Contains 4 A.T hook DNA-binding domains., subcellular location:Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus., subunit:Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex) ., tissue specificity:Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.
Description
Function: May play a role in transcriptional regulation interacting with ISWI. May serve a specific role in maintaining or altering the chromatin structure of the rDNA locus. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. sequence Caution: Contaminating sequence. Potential poly-A sequence. similarity: Belongs to the WAL family. similarity: Contains 1 bromo domain. similarity: Contains 1 DDT domain. similarity: Contains 1 MBD (methyl-CpG-binding) domain. similarity: Contains 1 PHD-type zinc finger. similarity: Contains 4 A. T hook DNA-binding domains. subcellular location: Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus. subunit: Together with SMARCA5, it forms a complex termed NoRC (nucleolar remodeling complex). tissue specificity: Expressed at moderate levels in most tissues analyzed, including heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.
Product Name Alternative
BAZ2A; KIAA0314; TIP5; Bromodomain adjacent to zinc finger domain protein 2A; Transcription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3
UniProt
Q9UIF9
Swiss Prot
Q9UIF9
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human BAZ2A. AA range:1281-1330
Target
Tip5
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
210kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
210kD
Fragment
IgG
Subcellular Location
Nucleus, nucleolus . Colocalizes with the basal RNA polymerase I transcription factor UBF in the nucleolus. .
Other Product Names
BAZ2A; KIAA0314; TIP5; Bromodomain adjacent to zinc finger domain protein 2A; Transcription termination factor I-interacting protein 5; TTF-I-interacting protein 5; Tip5; hWALp3
Gene ID (Human)
605682