ARRDC3 rabbit pAb

CAT: 0855-ES6920-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES6920-01Size:50 µL
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Background
This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor-related antigen, targeting the integrin for internalization and degradation. [provided by RefSeq, Jul 2016]
Description
This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor-related antigen, targeting the integrin for internalization and degradation. [provided by RefSeq, Jul 2016],
UniProt
Q96B67
Swiss Prot
Q96B67
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human ARRDC3. AA range:365-414
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
46kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
46kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Lysosome . Endosome . Early endosome . Associated with plasma membrane, as well as with endosomes and lysosomes during endocytosis (PubMed:16269462, PubMed:23208550, PubMed:20559325) . .
Other Product Names
ARRDC3; KIAA1376; Arrestin domain-containing protein 3; TBP-2-like inducible membrane protein; TLIMP
Gene ID (Human)
57561

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