NEDL2 rabbit pAb

• Background :

  Function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73., pathway:Protein modification; protein ubiquitination., similarity:Contains 1 C2 domain., similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain., similarity:Contains 2 WW domains., subunit:Interacts with TP73., tissue specificity:Predominantly expressed in adult brain, lung and heart.

• Description :

  Function: E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. pathway: Protein modification; protein ubiquitination. similarity: Contains 1 C2 domain. similarity: Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. similarity: Contains 2 WW domains. subunit: Interacts with TP73. tissue specificity: Predominantly expressed in adult brain, lung and heart.

• Product Name Alternative :

  HECW2; KIAA1301; NEDL2; E3 ubiquitin-protein ligase HECW2; HECT; C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2

• UniProt :

  Q9P2P5

• Swiss Prot :

  Q9P2P5

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human HECW2. AA range:481-530

• Target :

  NEDL2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  140-150kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  140-150kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Cytoplasm, cytoskeleton, spindle .

• Other Product Names :

  HECW2; KIAA1301; NEDL2; E3 ubiquitin-protein ligase HECW2; HECT; C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2

• Gene ID (Human) :

  57520