EDEM2 rabbit pAb

• Background:

  In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD) . EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]) .[supplied by OMIM, Mar 2008]

• Description:

  In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al. 2005 [PubMed 15537790]). [supplied by OMIM, Mar 2008],

• UniProt:

  Q9BV94

• Swiss Prot:

  Q9BV94

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from the C-terminal region of human EDEM2.

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Storage Conditions:

  -20°C/1 year

• Fragment:

  IgG

• Subcellular Location:

  Endoplasmic reticulum lumen .

• Other Product Names:

  EDEM2; C20orf31; C20orf49; ER degradation-enhancing alpha-mannosidase-like 2

• Gene ID (Human):

  55741