EDEM1 rabbit pAb

• Background :

  Function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity., similarity:Belongs to the glycosyl hydrolase 47 family., subunit:Interacts with DERL2 and DERL3.

• Description :

  Function: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity. similarity: Belongs to the glycosyl hydrolase 47 family. subunit: Interacts with DERL2 and DERL3.

• UniProt :

  Q92611

• Swiss Prot :

  Q92611

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from part region of human protein

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  72kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  72kD

• Fragment :

  IgG

• Subcellular Location :

  Endoplasmic reticulum membrane ; Single-pass type II membrane protein .

• Gene ID (Human) :

  9695