PMS2/PMS2CL rabbit pAb

CAT: 0855-ES6634-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES6634-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Caution:According to PubMed:15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed:17525332) . Given that the product described by PubMed:15077197 is located downstream and on another frame of the transcript, it may explain why PubMed:15256438 could not detect this protein on a Western blot., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Wrong choice of transcript., similarity:Belongs to the DNA mismatch repair mutL/hexB family.
Description
Caution: According to PubMed: 15077197, it is a pseudogene. However, a peptide specific to this protein was identified by mass spectrometry (PubMed: 17525332). Given that the product described by PubMed: 15077197 is located downstream and on another frame of the transcript, it may explain why PubMed: 15256438 could not detect this protein on a Western blot. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. sequence Caution: Wrong choice of transcript. similarity: Belongs to the DNA mismatch repair mutL/hexB family.
UniProt
Q68D20/P54278
Swiss Prot
Q68D20/P54278
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human PMS2CL. AA range:125-174
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Mismatch repair complex
Other Product Names
PMS2CL; Protein PMS2CL; PMS2-C terminal-like protein; PMS2; PMSL2; Mismatch repair endonuclease PMS2; DNA mismatch repair protein PMS2; PMS1 protein homolog 2
Gene ID (Human)
5395

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