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MxB rabbit pAb

CAT: 0855-ES6295-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6295-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008],
Product Name Alternative
MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein
UniProt
P20592
Swiss Prot
P20592
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from the Internal region of human MxB.
Target
MxB
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
82kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
82kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Nucleus, nuclear pore complex . Localization to nuclear pores requires GTP-binding.
Other Product Names
MX2; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; Myxovirus resistance protein 2; p78-related protein
Gene ID (Human)
4600

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