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MAZ rabbit pAb

CAT: 0855-ES6197-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6197-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors., similarity:Contains 6 C2H2-type zinc fingers., subcellular location:In brains of Alzheimer disease patients, present in a plaque-like structures., subunit:Interacts with BPTF., tissue specificity:Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level) .
Description
Function: May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. similarity: Contains 6 C2H2-type zinc fingers. subcellular location: In brains of Alzheimer disease patients, present in a plaque-like structures. subunit: Interacts with BPTF. tissue specificity: Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).
UniProt
P56270
Swiss Prot
P56270
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MAZ. AA range:159-208
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Molecular Weight
48kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
48kD
Fragment
IgG
Subcellular Location
Nucleus . In brains of Alzheimer disease patients, present in a plaque-like structures.
Other Product Names
MAZ; ZNF801; Myc-associated zinc finger protein; MAZI; Pur-1; Purine-binding transcription factor; Transcription factor Zif87; ZF87; Zinc finger protein 801
Gene ID (Human)
4150

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