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L-Histidine (Standard)

CAT: 0804-HY-N0832R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0832R-01Size:10 mg
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Description
L-Histidine (Standard) is the analytical standard of L-Histidine. This product is intended for research and analytical applications. L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
CAS Number
71-00-1
UNSPSC
12352005
Target
Endogenous Metabolite; Mitochondrial Metabolism; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-histidine-standard.html
Purity
99.97
Smiles
N[C@@H](CC1=CNC=N1)C(O)=O
Molecular Formula
C6H9N3O2
Molecular Weight
155.15
References & Citations
[1]Bou Zeidan M, et al. L-histidine inhibits biofilm formation and FLO11-associated phenotypes in Saccharomyces cerevisiae flor yeasts. PLoS One. 2014 Nov 4;9 (11) :e112141.|[2]Rama Rao KV, et al. Brain edema in acute liver failure: inhibition by L-histidine. Am J Pathol. 2010 Mar;176 (3) :1400-8.|[3]Yoshikawa T, et al. Insufficient intake of L-histidine reduces brain histamine and causes anxiety-like behaviors in male mice. J Nutr. 2014 Oct;144 (10) :1637-41.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

Chemical Information

L-Histidine

L-histidine is the L-enantiomer of the amino acid histidine. It has a role as a micronutrient, a nutraceutical, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a human metabolite and an algal metabolite. It is a L-alpha-amino acid, a histidine and a proteinogenic amino acid. It is a conjugate base of a L-histidinium(1+). It is a conjugate acid of a L-histidinate(1-). It is an enantiomer of a D-histidine. It is a tautomer of a L-histidine zwitterion.

CAS Number71-00-1
PubChem CID6274
IUPAC Name(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acid
Molecular FormulaC6H9N3O2
Molecular Weight155.15
XLogP-3.2
Topological Polar Surface Area92
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count11
Formal Charge0
Complexity151
SMILES
C1=C(NC=N1)C[C@@H](C(=O)O)N
InChI
InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
InChIKey
HNDVDQJCIGZPNO-YFKPBYRVSA-N
Chemical Structure
2D Structure
2D structure of L-Histidine
CAS: 71-00-1
CID: 6274
Formula: C6H9N3O2
MW: 155.15
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight155.15
XLogP3-3.2
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass155.069476538
Monoisotopic Mass155.069476538
Topological Polar Surface Area92 Ų
Heavy Atom Count11
Formal Charge0
Complexity151
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes