L-Histidine-15N3

L-Histidine-15N3

• CAS Number: 1217456-12-6
• UNSPSC Description: L-Histidine-15N3 is the 15N-labeled L-Histidine. L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
• Target Antigen: Endogenous Metabolite; Isotope-Labeled Compounds; Mitochondrial Metabolism
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease;Others
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease; Inflammation/Immunology; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/l-histidine-15n3.html
• Solubility: 10 mM in DMSO
• Smiles: OC([C@@H]([15NH2])CC1=C[15NH]C=[15N]1)=O
• Molecular Weight: 158.13
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Bou Zeidan M, et al. L-histidine inhibits biofilm formation and FLO11-associated phenotypes in Saccharomyces cerevisiae flor yeasts. PLoS One. 2014 Nov 4;9(11):e112141.|[3]Rama Rao KV, et al. Brain edema in acute liver failure: inhibition by L-histidine. Am J Pathol. 2010 Mar;176(3):1400-8.|[4]Yoshikawa T, et al. Insufficient intake of L-histidine reduces brain histamine and causes anxiety-like behaviors in male mice. J Nutr. 2014 Oct;144(10):1637-41.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported