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JAK3 rabbit pAb

CAT: 0855-ES5976-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5976-01Size:50 µL
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Background
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease) . [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in Cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],
UniProt
P52333
Swiss Prot
P52333
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human JAK3. AA range:751-800
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
125kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
125kD
Fragment
IgG
Subcellular Location
Endomembrane system ; Peripheral membrane protein . Cytoplasm .
Other Product Names
JAK3; Tyrosine-protein kinase JAK3; Janus kinase 3; JAK-3; Leukocyte janus kinase; L-JAK
Gene ID (Human)
3718