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Jak3 (phospho-Tyr980/981) rabbit pAb

CAT:
855-ES15392-02
Size:
100 μL
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
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Jak3 (phospho-Tyr980/981) rabbit pAb

  • Description: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in Cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],
  • Synonyms: Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)
  • Gene ID: 3718
  • UniProt: P52333
  • Cellular Locus: Endomembrane system ; Peripheral membrane protein. Cytoplasm.
  • Host: Rabbit
  • Species Reactivity: Human, Mouse
  • Immunogen: Synthesized phosho peptide around human Jak3 (Tyr980 and 981)
  • Clonality: Polyclonal
  • Validated Applications: WB, IHC
  • Stability: 1 year
  • Concentration: 1 mg/mL
  • Dilution: WB 1:500-2000;IHC-p 1:50-300
  • Molecular Weight: 125kD
  • Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

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