SERGEF rabbit pAb

• Background :

  Function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 7 RCC1 repeats., subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.

• Description :

  Function: Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Contains 7 RCC1 repeats. subunit: Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.

• UniProt :

  Q9UGK8

• Swiss Prot :

  Q9UGK8

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human SERGEF. AA range:179-228

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Molecular Weight :

  50kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  50kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Nucleus .

• Other Product Names :

  SERGEF; DELGEF; GNEFR; Secretion-regulating guanine nucleotide exchange factor; Deafness locus-associated putative guanine nucleotide exchange factor; DelGEF; Guanine nucleotide exchange factor-related protein

• Gene ID (Human) :

  26297