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KCNC3 rabbit pAb

CAT: 0855-ES15348-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES15348-01Size:50 µL
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Background
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Alternate splicing results in several transcript variants. [provided by RefSeq, Mar 2014]
Description
The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Alternate splicing results in several transcript variants. [provided by RefSeq, Mar 2014],
UniProt
Q14003
Swiss Prot
Q14003
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human KCNC3 AA range: 303-353
Target
KCNC3
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, presynaptic cell membrane ; Multi-pass membrane protein . Perikaryon . Cell projection, axon . Cell projection, dendrite . Cell projection, dendritic spine membrane ; Multi-pass membrane protein . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Detected on Purkinje cell dendritic spines, positioned perisynaptically but also in extrasynaptic positions along the spine membranes (By similarity) . Detected at presynaptic calices of Held (By similarity) . Colocalizes with the cortical actin cytoskeleton and the Arp2/3 complex (PubMed:26997484) . .
Gene ID (Human)
3748

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