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NHE-8 rabbit pAb

CAT: 0855-ES5330-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5330-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al., 2008 [PubMed 18209477]) .[supplied by OMIM, Apr 2009]
Description
Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al. 2008 [PubMed 18209477]). [supplied by OMIM, Apr 2009],
UniProt
Q9Y2E8
Swiss Prot
Q9Y2E8
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC9A8. AA range:451-500
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000.IHC-p:1:50-300 ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
65kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
65kD
Fragment
IgG
Subcellular Location
Golgi apparatus membrane ; Multi-pass membrane protein .
Other Product Names
SLC9A8; KIAA0939; NHE8; Sodium/hydrogen exchanger 8; Na (+) /H (+) exchanger 8; NHE-8; Solute carrier family 9 member 8
Gene ID (Human)
23315

UniProtKB · Q9Y2E8

Sodium/hydrogen exchanger 8

SL9A8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y2E8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC9A8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DTQ8, Q2M1U9, Q68CZ8, Q9BX15, Q9Y507
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

AntiportDifferentiationIon transportSodium transportSpermatogenesisTransport

Cellular component

Cell membraneCytoplasmic vesicleEndosomeGolgi apparatusMembrane

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Ligand

Sodium

Domain

TransmembraneTransmembrane helix

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