ZnT-8 rabbit pAb
CAT:
855-ES4993-01
Size:
50 μL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
ZnT-8 rabbit pAb
- Description: The protein encoded by this gene is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. This gene is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin-dependent (NIDDM). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
- Synonyms: SLC30A8; ZNT8; Zinc transporter 8; ZnT-8; Solute carrier family 30 member 8
- Gene ID: 169026
- UniProt: Q8IWU4
- Cellular Locus: Cell membrane ; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane ; Multi-pass membrane protein. Associated with insulin and glucagon secretory granules..
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: The antiserum was produced against synthesized peptide derived from human SLC30A8. AA range:171-220
- Clonality: Polyclonal
- Validated Applications: WB, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Molecular Weight: 41kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.