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PDZK3 rabbit pAb

CAT: 0855-ES5297-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5297-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16) . Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015]
Description
The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. [provided by RefSeq, Dec 2015],
Product Name Alternative
PDZD2; AIPC; KIAA0300; PDZK3; PDZ domain-containing protein 2; Activated in prostate cancer protein; PDZ domain-containing protein 3
UniProt
O15018
Swiss Prot
O15018
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PDZD2. AA range:51-100
Target
PDZK3
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Endoplasmic reticulum . At cell-cell contacts in lung epithelial cells. .; [Processed PDZ domain-containing protein 2]: Secreted .
Other Product Names
PDZD2; AIPC; KIAA0300; PDZK3; PDZ domain-containing protein 2; Activated in prostate cancer protein; PDZ domain-containing protein 3
Gene ID (Human)
23037

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