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TPX2 rabbit pAb

CAT: 0855-ES5280-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5280-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Developmental stage:Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., subcellular location:During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus., tissue specificity:Expressed in lung carcinoma cell lines but not in normal lung tissues.
Description
Developmental stage: Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. subcellular location: During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. tissue specificity: Expressed in lung carcinoma cell lines but not in normal lung tissues.
Product Name Alternative
TPX2; C20orf1; C20orf2; DIL2; HCA519; Targeting protein for Xklp2; Differentially expressed in cancerous and non-cancerous lung cells 2; DIL-2; Hepatocellular carcinoma-associated antigen 519; Protein fls353; Restricted expression prolifera
UniProt
Q9ULW0
Swiss Prot
Q9ULW0
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human DIL-2. AA range:301-350
Target
TPX2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
86kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
86kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole . During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules. .
Other Product Names
TPX2; C20orf1; C20orf2; DIL2; HCA519; Targeting protein for Xklp2; Differentially expressed in cancerous and non-cancerous lung cells 2; DIL-2; Hepatocellular carcinoma-associated antigen 519; Protein fls353; Restricted expression prolifera
Gene ID (Human)
22974

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