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CELSR3 rabbit pAb

CAT: 0855-ES5051-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5051-02Size:100 µL
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Background
This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013]
Description
This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013],
Product Name Alternative
CELSR3; CDHF11; EGFL1; FMI1; KIAA0812; MEGF2; Cadherin EGF LAG seven-pass G-type receptor 3; Cadherin family member 11; Epidermal growth factor-like protein 1; EGF-like protein 1; Flamingo homolog 1; hFmi1; Multiple epidermal growth factor-
UniProt
Q9NYQ7
Swiss Prot
Q9NYQ7
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CELSR3. AA range:3195-3244
Target
CELSR3
Clonality
Polyclonal
Source
Rabbit
Applications
IF; ELISA
Concentration
1 mg/ml
Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
CELSR3; CDHF11; EGFL1; FMI1; KIAA0812; MEGF2; Cadherin EGF LAG seven-pass G-type receptor 3; Cadherin family member 11; Epidermal growth factor-like protein 1; EGF-like protein 1; Flamingo homolog 1; hFmi1; Multiple epidermal growth factor-
Gene ID (Human)
1951

UniProtKB · Q9NYQ7

Cadherin EGF LAG seven-pass G-type receptor 3

CELR3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NYQ7
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CELSR3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
O75092
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

Calcium

Cellular component

Cell membraneMembrane

Molecular function

Developmental proteinG protein-coupled receptorReceptorTransducer

PTM

Disulfide bondGlycoproteinHydroxylationPhosphoprotein

Domain

EGF-like domainLaminin EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Technical term

Proteomics identificationReference proteome

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