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Repetin rabbit pAb

CAT: 0855-ES4722-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4722-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Domain:Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats., function:Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase., similarity:Belongs to the S100-fused protein family., similarity:Contains 2 EF-hand domains., tissue specificity:Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.
Description
Domain: Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats. function: Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. PTM: Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase. similarity: Belongs to the S100-fused protein family. similarity: Contains 2 EF-hand domains. tissue specificity: Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.
Product Name Alternative
RPTN; Repetin
UniProt
Q6XPR3
Swiss Prot
Q6XPR3
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RPTN. AA range:648-697
Target
Repetin
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Buffer
-20°C/1 year
Molecular Weight
90kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
90kD
Fragment
IgG
Subcellular Location
Secreted, extracellular space, extracellular matrix.
Other Product Names
RPTN; Repetin
Gene ID (Human)
126638

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