MALT1 rabbit pAb

• Background :

  This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

• Description :

  This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

• UniProt :

  Q9UDY8

• Swiss Prot :

  Q9UDY8

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human MALT1. AA range:301-350

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  90kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  90kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, perinuclear region . Nucleus . Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10. .

• Other Product Names :

  MALT1; MLT; Mucosa-associated lymphoid tissue lymphoma translocation protein 1; MALT lymphoma-associated translocation; Paracaspase

• Gene ID (Human) :

  10892