JAM-A rabbit pAb

CAT: 0855-ES4209-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES4209-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
Description
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008],
Product Name Alternative
F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321
UniProt
Q9Y624
Swiss Prot
Q9Y624
Reactivity
Human; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human F11R. AA range:191-240
Target
JAM-A
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
32kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
32kD
Fragment
IgG
Subcellular Location
Cell junction, tight junction . Cell membrane ; Single-pass type I membrane protein . Localized at tight junctions of both epithelial and endothelial cells. .
Other Product Names
F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321
Gene ID (Human)
50848

Related Products

CatalogName
ES9186-01JAM3 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20599-01VEGF Rabbit rabbit pAb
ES20825-01ATG7 Rabbit rabbit pAb
ES20596-01WIPI2 Rabbit rabbit pAb
ES20659-01NBR1 Rabbit rabbit pAb
ES20831-01ATG13 Rabbit rabbit pAb

Alternative Products

CatalogName
MBS8540158-01JAM-A Rabbit pAb
NBP2-68604Rabbit Polyclonal JAM-B/VE-JAM Antibody
MBS8111608-01Anti-JAM-2/JAM-B Antibody, Rabbit Polyclonal
MBS9146510-01JAM-A/CD321 Rabbit pAb
A03018-50JAM A Antibody, mAb, Rabbit
E53P02587JAM-A Rabbit Polyclonal Antibody
E49Y5635JAM A Rabbit Monoclonal Antibody
E2251409JAM-B Rabbit pAb
NBP2-38934Rabbit Polyclonal JAM-A Antibody
MBS9512337-01JAM-B Rabbit Polyclonal Antibody

Popular Products