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DRA rabbit pAb

CAT: 0855-ES4147-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4147-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008]
Description
The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008],
Product Name Alternative
SLC26A3; DRA; Chloride anion exchanger; Down-regulated in adenoma; Protein DRA; Solute carrier family 26 member 3
UniProt
P40879
Swiss Prot
P40879
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the C-terminal region of human DRA.
Target
DRA
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
84kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
84kD
Fragment
IgG
Subcellular Location
Apical cell membrane ; Multi-pass membrane protein . Membrane ; Multi-pass membrane protein . Localized in sperm membranes. Midpiece of sperm tail. Colocalizes with CFTR at the midpiece of sperm tail (By similarity) . .
Other Product Names
SLC26A3; DRA; Chloride anion exchanger; Down-regulated in adenoma; Protein DRA; Solute carrier family 26 member 3
Gene ID (Human)
1811

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