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ATP1AL1 rabbit pAb

CAT: 0855-ES3829-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3829-01Size:50 µL
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Background
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H (+) and K (+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Description
The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H (+) and K (+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],
Product Name Alternative
ATP12A; ATP1AL1; Potassium-transporting ATPase alpha chain 2; Non-gastric H (+) /K (+) ATPase subunit alpha; Proton pump
UniProt
P54707
Swiss Prot
P54707
Reactivity
Human; Rat
Immunogen
Synthesized peptide derived from ATP1AL1 . at AA range: 380-460
Target
ATP1AL1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
115kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
115kD
Fragment
IgG
Subcellular Location
Apical cell membrane ; Multi-pass membrane protein .
Other Product Names
ATP12A; ATP1AL1; Potassium-transporting ATPase alpha chain 2; Non-gastric H (+) /K (+) ATPase subunit alpha; Proton pump
Gene ID (Human)
479

UniProtKB · P54707

Potassium-transporting ATPase alpha chain 2

AT12A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P54707
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ATP12A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q13816, Q13817, Q16734, Q5W035, Q8N5U2
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-bindingPotassiumSodium

Cellular component

Cell membraneMembrane

Biological process

Hydrogen ion transportIon transportPotassium transportSodium transportTransport

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Molecular function

Translocase

Domain

TransmembraneTransmembrane helix

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