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Aladin rabbit pAb

CAT: 0855-ES3772-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3772-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Description
The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
Product Name Alternative
AAAS; ADRACALA; GL003; Aladin; Adracalin
UniProt
Q9NRG9
Swiss Prot
Q9NRG9
Reactivity
Human; Rat
Immunogen
Synthesized peptide derived from Aladin . at AA range: 360-440
Target
Aladin
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
59kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
59kD
Fragment
IgG
Subcellular Location
Nucleus, nuclear pore complex . Cytoplasm, cytoskeleton, spindle pole . Nucleus envelope . In metaphase cells localizes within the spindle with some accumulation around spindle poles, with the highest concentration between the centrosome and metaphase plate (PubMed:26246606) . The localization to the spindle is microtubule-mediated (PubMed:26246606) . .
Other Product Names
AAAS; ADRACALA; GL003; Aladin; Adracalin
Gene ID (Human)
8086

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